Research White Papers

A lipoxygenase inhibitor in breast cancer

A 39-year-old woman presented with symptoms of headache and nausea to her physician. She had been operated on 1 year earlier for primary breast cancer, stage I, with no metastases or lymph node involvement, followed by a monotherapy study with trastuzamab because of her tumor’s HER2 positive receptors. Following a negative physical examination further staging included a tumor marker evaluation and a computed tomography (CT) scan for her head.

Medullary thyroid carcinoma relapse reversed

Medullary thyroid carcinoma (MTC) is a rare calcitonin-pro- ducing neuroendocrine tumor arising from neural crest-derived parafollicular C cells (calcitonin-producing cells) of the thyroid gland, a component of multiple endocrine neoplasia type 2 or MEN2 syndromes, accounting for approximately 4% of all thyroid cancers. Although 25-30% of MTC cases are inher- ited disorders, the remaining cases consist of sporadic forms of the disease.

Non Hodgkin’s Lymphoma reversal with Dichloroacetate

Non Hodgkin’s lymphoma is a disease of the lymph system that responds well to therapies including chemotherapy and radiation. Newer therapies, that are more aggressive, include chemotherapy with whole body radiation, followed by stem cell transplants. They have resulted in cures in some patients. Other patients, however, aware of the compromise on the quality of life with more aggressive therapies seek new avenues of treatment themselves.